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Formation of chitosan nanoparticles to encapsulate krill oil (Euphausia superba) for application as a dietary supplement

Haidera, Junaid, Majeed, Hamid, Williams, Peter A, Safdar, Waseem and Zhong, Fang (2016) Formation of chitosan nanoparticles to encapsulate krill oil (Euphausia superba) for application as a dietary supplement. Food Hydrocolloids, 63. pp. 27-34. ISSN 0268-005X

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Abstract

Encapsulation of krill oil (KO), a rich source of eicosapentanoic (EPA) and docosahexanoic acid (DHA) was carried out in chitosan-TPP (tripolyphosphate) nanoparticles using a newly developed two-step process (i.e, formation of emulsion and later electrostatic interaction of chitosan with TPP). The encapsulation of KO in chitosan nanoparticles (CSNPs) was confirmed by using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and Thermo gravimetric analysis (TGA) techniques. Loading capacity (LC) and encapsulation efficiency (EE) of the obtained particles were about 9 – 25 and 33 – 59 % respectively, when the initial KO content was in the ratio of 0.25 – 1.25 g/g of Chitosan. Bulk KO showed less protection to oxidation and showed more formation of hydroperoxides during first week as noted by FTIR. However, KO loaded CSNPs showed better prevention of KO towards oxidation with less hydroperoxide formation even after two weeks of storage at elevated temperature (45 oC). The obtained KO-loaded CSNPs were irregular in shape with an average particle diameter of < 130 nm as observed by SEM. The results obtained confirmed the suitability of the emulsion and later electrostatic interaction of CS with TPP for the formation of KO loaded CSNPs with greater EE & LC, which will enhance their usage in the Food and Pharmaceutical industries

Item Type: Article
Keywords: Krill Oil, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Thermo gravimetric analysis (TGA), Oxidative stability
Divisions: Applied Science, Computing and Engineering
Depositing User: Mr Stewart Milne
Date Deposited: 25 Aug 2016 15:13
Last Modified: 19 Dec 2017 14:29
URI: http://glyndwr.collections.crest.ac.uk/id/eprint/10167

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